The core idea of this project is to create a bionic invisible pancreas (BIP), a radically new device, uniquely capable to exploit physiological glucose sensing and hormones delivery route. The BIP will enable intraperitoneal insulin delivery for optimal glycaemic control. Leveraging this, BIP will restore glucose regulation in subjects with diabetes as in healthy individuals.
This movie represents some key concepts, but the surgical positioning of the implant, its dimensions and several technical details do not match the ones that will be really pursued in the project course.
The architecture of BIP encompasses a ground-breaking, lifelong lasting implanted ip glucose nanosensor; a radically novel ip hormone delivery pump, with unique non-invasive hormone refill with a magnetic docking pill and non-invasive wireless battery recharge; an intelligent closed-loop hormone dosing algorithm, optimized for ip sensing and delivery, individualized, adaptive and equipped with advanced self-diagnostic algorithms.
Pump refilling through a weekly oral recyclable drug pill will free T1D subjects from the burden of pain and awkward daily measurement and treatment actions. Wireless power transfer and data transmission to cloud-based data management system round-up to a revolutionary treatment device for this incurable chronic disease. key feature of BIP is to be fully-implantable and life-long lasting thanks to novel biocompatible and immune-optimized coatings guaranteeing long-term safety and stability
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